Dr. Patrick James Hughes
MBBS, FFARACS, FANZCA
Information for Patients Undergoing Sedation or Anaesthesia for Oral or Maxillofacial Surgery click here
- 1. Contact Details
- 2. Qualifications and Professional Accreditation Details
- 3. Affiliations
- 4. Previous Professional Experience
- 5. Publications
- 6. Professional Associations
- 7. Other Interests
Publications
- Advances in Pharmacology applied in Maxillofacial Anaesthesia click here
Hughes PJ, Brown TCK. An approach to posterior femoral cutaneous nerve block. Anaesth Intens Care 1986; 14:350-351
Hughes PJ. Propofol in acute porphyrias (letter).Anaesthesia 1990; 45: 415
Hughes PJ, Doherty MM, Charman WN. A rabbit model for the evaluation of epidurally administered local anaesthetic agents. Anaesth Intens Care 1993; 21: 298-303
Doherty MM, Hughes PJ, Kim SR, Mainwaring DE, Charman WN. Effect of lyophilization on the physical characteristics of medium molecular mass hyaluronates. Int J Pharm 1994; 111: 205-211
Doherty MM, Hughes PJ, Korszniak N, Charman WN. Prolongation of lidocaine induced epidural anesthesia by medium molecular weight hyaluronic acid: Pharmacodynamic and Pharmacokinetic factors in the rabbit. Anesth Analg 1995;80: 740-746
Hughes PJ, Charman WN, Doherty MM. Depth of epidural injection in rabbits (letter). Anaesth Intens Care 1995 ; 23: 119
Murrell GC, Hughes PJ. The Cochrane Collaboration (letter). Anaesth Intens Care 1996; 24: 286-287
Murrell GC, Leake T, Hughes PJ. A comparison of ketorolac and indomethacin used for post-operative analgesia following laparoscopic surgery in day patients. Anaesth Intens Care 1996; 24: 237-240
Doherty MM, Hughes PJ, Charman SA, Brock KV, Korszniak NV, Charman WN. Biphasic Dr.ug absorption from the epidural space of the dog may limit the utility of a slow release medium molecular weight hyaluronic acid-lidocaine ionic complex formulation. Anesth Analg 1996; 83: 1244-1250
Hughes PJ, Mackay P. Postobstructive pulmonary oedema- A case series and review- Reply (letter). Anaesth Intens Care 2001; 29:79-80
Hughes PJ, Mackay P. Sedation for endoscopy: the safe use of propofol by general practitioners (letter). MJA 2002; 177: 164-165
Published Abstracts (4):
Hughes PJ. Nerve blocks around the thigh. Can Anaesth Soc J 1985; 32: S76
Doherty MM, Hughes PJ, Charman WN. Pharmacokinetics and Pharmacodynamics of lignocaine and bupivicaine in a rabbit epidural analgesia model. Clin Exp Pharmacol & Physiol; 1990 S18
Charman WN, Doherty MM, Hughes PJ. Evaluation of selected solution and viscous local anaesthetic formulations in a rabbit model of epidural analgesia. Pharmaceutical Res 1991; 8: S-244
Doherty MM, Korszniak N, Hughes PJ, Charman WN. Evaluation of sustained release epidural lidocaine formulations in the rabbit and dog. Pharmaceutical Res 1994; 11: S-313
Research Funding/Grants/Patent Application
1989-90 Local anaesthetic formulation design Pharmasearch Ltd. Melbourne $4500
1991-93 Design and evaluation of novel local anaesthetic and analgesic formulations Sigma Pharmaceuticals $151000
Provisional Australian patent application PK 28940/ 90 "Pharmaceutical composition" Filed October 16th 1990 by Hughes PJ & Charman WN Refiled March 18th 1992 PL 1409/92
Awards
MOBIUS AWARD 1989 U.S. Television & Radio Commercials Festival Medical Advisor to HDM Mattingly and Cohorts P/L in the production of the public service commercial entitled "Belt Up" for the Road Traffic Authority Victoria
Other Medical Interests
Hyperbaric and Underwater medicine: RAN School of Underwater Medicine HMAS Penguin Sydney 1983
Anaesthesia in developing countries: Interplast programmes to Lautoka, Fiji April 1988 and March 1989
Victorian Consultative Council on Anaesthetic Mortality and Morbidity Member 1997-2007